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  • About ATTR amyloidosis
    • Overview
    • Signs and symptoms
    • Diagnosis
  • Phenotyping HF
  • Referral
  • Management approaches
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Transthyretin amyloidosis (ATTR) is a systemic, progressive and potentially fatal disease that is frequently under-recognised due to its non-specific and heterogenous manifestations1–3
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Early suspicion can lead to timely diagnosis of ATTR amyloidosis and prompt treatment, which may slow disease progression1,4–6

If you suspect ATTR amyloidosis, it is important to refer your patients to the National Amyloidosis Centre to be assessed

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It is important to suspect ATTR amyloidosis signs and symptoms to facilitate earlier diagnosis and treatment1

Recognise the signs and symptoms of ATTR amyloidosis

SEE THE SIGNS AND SYMPTOMS

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In most patients with ATTR-CM, misdiagnosis or delayed diagnosis may lead to irretrievable loss of quality of life and disease progression of polyneuropathic and cardiac symptoms1,6

Early diagnosis and referral are essential

DISCOVER DIAGNOSTIC TOOLS

ATTR=transthyretin amyloidosis; ATTR-CM=transthyretin amyloidosis with cardiomyopathy.

References: 1. Nativi-Nicolau JN, et al. Heart Fail Rev. 2022;27(3):785–793; 2. Adams D, et al. J Neurol. 2021;268(6):2109–2122; 3. Gertz MA, et al. BMC Fam Pract. 2020;21(1):198; 4. Gonzàlez-Duarte, et al. Neuro Ther. 2020;9:135–149; 5. Keohane D, et al. Amyloid. 2017;24(1):30–36; 6. Rozenbaum MH, et al. J Comp Eff Res. 2021;10(11):927–938.

GB-62815 I April 2025

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